The Pacbio – Short-read Sequencing – Onso System is an innovative benchtop short-read DNA sequencing platform with an extraordinary level of accuracy using PacBio sequencing by binding (SBB) technology. Ultra-high Q40+ data quality allows you to break through limits of detection.

The Onso short-read sequencing system is a scalable and flexible benchtop platform that provides an extraordinary level of accuracy through its unique sequencing by binding (SBB™) technology. With inherently lower sequencing noise, the Onso system enables researchers to uncover rare variants previously missed and do so at lower sequencing depths.

The accuracy provided by the Onso system will help drive groundbreaking discoveries in areas such as liquid biopsy testing for minimal residual disease (MRD), antibiotic resistance monitoring in microbial communities, off-target analysis in gene editing experiments, and many other “needle-in-a-haystack” applications where the highest level of sensitivity is desired.

Available Models Key Industries

The new advanced Postnova CF2000 Series was developed to become the first professional modular Centrifugal FFF system available. It is completely controled by the NovaFFF single software platform which runs the entire system from autosampler to detectors. The CF2000 Centrifugal FFF incorporates the combined proven know-how and the technologies from three decades of leadership in FFF. Due to its unique design, the CF2000 Centrifugal FFF system offers more flexibility, higher robustness and better performance than traditional particle sizer systems. The CF2000 allows high resolution particle separation and sizing at the same time and consequently sets a complete new standard and offers a real alternative to traditional particle characterization techniques.

The new Postnova SC2000 Modular SEC system offers unrivalled flexibility in Advanced SEC/GPC analysis. It is the first truly modular multi-detector SEC system available allowing flexible access to a wide range of applications. The system incorporates state-of-the-art detection technologies including light scattering (MALS > multi-angle light scattering) for absolute molecular weight and Viscosity detection for structural and conformational data. Many other detector and accessory options and combinations are available to build a system uniquely tailored to your application requirements, with the benefit of modularity to allow easy future expansion. In addition, the SC2000 can be further expanded to include FFF modules to widen the application range and allow both SEC and FFF separations to be carried out on the same sample within one instrument platform. Postnova has drawn on over three decades of cutting-edge separations leadership to design a solid stable SEC platform for you to achieve maximum success with your applications.

The new award winning Postnova TF2000 Thermal FFF Series was invented to become the first professional modular Thermal FFF system available. It is completely integrated by the NovaFFF single software platform which runs the entire system from autosampler to detectors. The TF2000 Series incorporates the combined solid know-how and the proven technologies from three decades of leadership in FFF. Due to its unique design, the TF2000 Thermal FFF system offers more flexibility, higher robustness and better performance than traditional chromatographic systems. No separation column with stationary phase is required anymore and consequently the TF2000 technology sets a complete new standard and offers a real alternative to column-based polymer characterization techniques.

Available Models Key Industries

Available Models Key Industries

AF2000 MF High Temperature Flow FFF Thermostat Module with integrated autosampler, channel and detector oven compartment and electronics unit, for advanced separation and characterization of polyolefin polymers, such as Polyethylene and Polypropylene. Temperature Range: Ambient to 220°C; Molar Mass Range: 10e3 to 10e12 Da; Particle Size Range 1 nm to 1000 nm. System comprising of one single integrated chassis inclunding moveable high temperature autosampler rack (25 sample vials, 5 mL volume) in lower system section, high temperature oven compartment for Flow FFF channels and detectors in the upper section, large top door for easy opening and access to channel and detectors as well as control electronics in the back part of the instrument and special Thermostat Control software connected to and running automated with NovaFFF. System can be equipped with various online high temperature detectors, which have to selected optional, such as High Temperature Infrared (HT-IR), Refractive Index (HT-RI), Multi-Angle Static Light Scattering (HT-MALS) and Viscometry (HT-VISCO). Additional Required Components: 1) High Temperature Flow FFF channel cartridge; 2) High Temp IR and/or additional detectors; 3) Control PC for NovaFFF and Thermostat Control software.

The PN5300 automatic sample injector includes the latest state-of-the-art auto injector technology, such as a double needle with positive headspace pressure, extensive wash routines for minimal carry over and three injection modes including micro liter pick-up mode for zero sample loss, huge injection range and full biocompatibility. Offering space for two deep well, shallow well or vial rack adapter plates, the PN5300 is ideally suited to be integrated with a wide range of different FFF systems. The newly designed Peltier cooling/heating keeps samples stable in a closed environment for maximum reproducibility. The temperature range from 4°C up to 40°C prevents degradation, evaporation or precipitation of sample during storage and processing with any FFF system.

With the introduction of the SF2000 G Postnova has launched a new type of Gravitational Splitt FFF. The SF2000 G is a the first true completely integrated and modular commercial G-Splitt including online optical particle detection. The machine can be used to separate, fractionate, purify and to characterize microparticles in one step. The attached PN3000 XPT detector allows determination of size and shape of the particle fractions eluting from the channel.

The system features a broad separation range from 1 to 300 µm depending on sample nature and has the ability to separate different shaped particle fractions from each other. The SF2000 G is clearly setting a new standard in the area of microparticle fractionation and marks a real break-through in Splitt science.

The system is using Postnovas unique G-Splitt FFF channel which can be re-used and cleaned after operation. Special pumps deliver and control all necessary in- and outlet flows and the attached PN3000 XPT detector provides further information about the particle fractions via its powerful software.

Quantabio reverse transcription reagents combine advanced qScript reverse transcriptase technology in a variety of stabilized, user-friendly formulations that deliver highly reproducible and sensitive RNA detection across a broad range of RNA input.

Our scientists were the first to successfully develop a comprehensive 1-tube reverse transcriptase reagent with sensitivity and linear dynamic range equivalent to traditional component reaction assembly. Quantabio’s new qScript XLT reagents continue to push the envelope of limit of detection (LOD) sensitivity and reproducibility.

Available in a variety of optimized formulations designed to support specific PCR applications and starting materials.

Quantabio PCR reagents are formulated with ultrapure AccuStart DNA polymerase, which contains a stringent antibody hotstart to ensure specific and efficient primer extension only after activation at 94°C.  Our enzymes are rigorously purified to remove host E. coli genomic DNA and are ideally suited for applied testing applications such as bacterial pathogen detection where residual host DNA in typical recombinant enzyme preparations can limit assay sensitivity and obscure detection of low copy targets.

Non-specific extension of primers at low temperature is a common cause of PCR artifacts and poor assay specificity and sensitivity.

Q uses a patented magnetic induction technology to rapidly heat samples coupled with fan forced air for cooling to acquire data in only 25 minutes. Available as a 4 channel model, the robust optical system acquires all channels simultaneously and allows for running the fastest multiplexed assays.

Q is exceptionally portable and versatile, without the need for calibration. It scales efficiently, handling up to 48 samples per run, and multiple units can connect wirelessly to a single computer via Bluetooth for processing up to 480 samples simultaneously.

Q’s distinctive spinning aluminum rotor ensures precise temperature control (± 0.05°C), outperforming traditional block-based thermal cyclers with multiple peltier heating blocks that may cause sample variations. This innovation enhances reproducibility and repeatability and enables the detection of 2-fold gene expression differences and precise identification of class IV SNP’s with 0.1°C melt temperature resolution.

PerfeCTa qPCR Reagents combine a stringent, ultrapure antibody hotstart with performance engineered DNA polymerase in stabilized 1-tube formulations optimized for the specific performance needs of real-time quantitative PCR.  Proprietary additives help eliminate persistent bubbles to enable efficient vortex mixing and fewer technical replicates thereby conserving precious sample. Adaptive buffer chemistry accommodates most assay designs and can be used with existing assay designs. PerfeCTa qPCR ToughMix reagents contain proprietary inhibitor-neutralizing additives that relieve several types of PCR inhibition ensuring reliable qPCR assay performance with clinical, plant or environmental specimens or complex food matix.